URSA B

AI benchmark

Built by
Insilico Medicine
Tier
B why
Snapshot

Open benchmark ↗github.com/insilicomedicine/URSA

What is URSA?

URSA benchmarks retrosynthesis systems and LLMs on synthesis planning for novel drug-like target molecules, scoring routes for stock termination and chemical plausibility.

  • Health and bio mostly

    “Synthesis planning aiming to find pathways of reactions for a target molecule is one of the most important and challenging tasks in drug discovery.”
    arxiv.org/abs/2607.04688v1 ↗
  • Science

    “benchmark the synthetic routes not only from a formal perspective, such as convergence to commercially available starting materials, but also from a chemical plausibility perspective”
    arxiv.org/abs/2607.04688v1 ↗

Who built URSA

Led by Insilico Medicine.

    Paper: arxiv.org/abs/2607.04688v1 ↗

    Tier B

    B

    Established: 15 or more models scored, or curated RL directories rate it.

    How much stands behind a tier: usage, who backs it, a confirmed line from its own site or paper, and a clear read on X. High with three of the four, medium with two, low otherwise.

    • 15 models scored
    • in curated RL directories (1 pt)
    How we got to tier B
    1. Adoption: 15 models scored. Tier B.
    2. Not yet read on X.
    3. In curated RL directories: 1 point, a floor of none.
    4. Confirmed: a line from its own site or paper places it.

    A clear view on X moves a tier one step up or down; most entries don't move. How tiers work.

    Where URSA sits

    Its domain on the map, live. Hover a logo for its name; click to open it. Open it on the full map

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    Next: browse all benchmarks. Entry from the RL Research daily scrape of public sources, 2026-10-19 snapshot.